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Year : 2014  |  Volume : 2  |  Issue : 1  |  Page : 15-17

Cross-sectional study of macular thickness variations in unilateral amblyopia

Department of Ophthalmology, King Georges' Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Siddharth Agrawal
Department of Ophthalmology, King Georges' Medical University, Lucknow - 226 003, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2320-3897.122630

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Aim: The aim of this study is to compare the mean macular thickness between normal and amblyopic eyes in unilateral strabismic and anisometropic amblyopia. Materials and Methods: A spectral domain-optical coherence tomography (Carl Zeiss Meditech, Inc.) was used to evaluate 51 patients (mean age 11.63 ± 2.84 years) with unilateral strabismic (n = 29) and anisometropic (n = 22) amblyopia. Data between the two eyes were compared using a paired t-test and a P value <0.05 was considered as significant. Results: Mean best-corrected visual acuity was +0.53 LogMAR (range 0.2-1.0) in the amblyopic eye. Mean macular thickness in the amblyopic eyes was 277.5 μ ± 15.3 and in the fellow normal eyes was 272.4 μ ± 13.1 (P < 0.05). On subgroup analysis, the difference was statistically significant in strabismic (P = 0.01) and not significant in anisometropic amblyopia (P = 0.08). Conclusion: The mean macular thickness was greater in amblyopic eyes as compared to the normal fellow eyes, and this difference was significant in strabismic amblyopia, but not significant in anisometric amblyopia.

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