| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 9
| Issue : 2 | Page : 64-66 |
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Corneal biomechanics in connective tissue disorders
Divya Kesarwani1, Vaibhav Kumar Jain1, Rachna Agarwal1, Jaya Kaushik2, Kumudini Sharma1
1 Department of Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2 Department of Ophthalmology, Armed Forces Medical College, Pune, Maharashtra, India
Correspondence Address:
Vaibhav Kumar Jain
Department of Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - 226 014, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jcor.jcor_74_20
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Purpose: The purpose of this study is to determine the corneal biomechanical properties in patients with connective tissue disorders (CTDs) and compare them with age-matched healthy control. Materials and Methods: In this cross-sectional study, 62 patients (study group) with CTDs and 44 healthy patients (control) were analyzed by Ocular Response Analyzer (Reichert Inc., Depew, N. Y., USA) and Corneal Pachymetry (SP-2000, Tomey, Nagoya, Japan). The right eye of all patients was assessed for corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPc), and Goldmann-correlated intraocular pressure (IOPg), and central corneal thickness (CCT). Results: Mean CH (9.54 ± 1.66 mm Hg [study group] and 10.62 ± 1.21 mm Hg [control]; P = 0.013) and mean CRF (9.95 ± 1.47 mm Hg [study group] and 10.76 ± 1.25 mm Hg [control]; P = 0.040) were significantly different between groups. Mean IOPc, IOPg, and CCT were not significantly different between groups. In the subgroup analysis of study cases (oral steroid versus nonsteroid therapy) of CTDs, CRF which was significantly lower in steroid (9.25 mm Hg) compared nonsteroid therapy (10.20 mm Hg) (P = 0.045), whereas, other parameters such as CCT, CH, IOPc, and IOPg were comparable between the two groups (P ≥ 0.05). Conclusion: CH is altered in CTDs which may be an independent risk factor for glaucoma and might underestimate intraocular pressure so CH is an important consideration in patients with CTDs.s
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