Home Print this page Email this page Users Online: 391
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2022  |  Volume : 10  |  Issue : 3  |  Page : 118-123

Assessment 20% oral dextrose induced analgesia during screening for retinopathy of prematurity


Department of Ophthalmology, Yenepoya Medical College, Deralakatte, Karnataka, India

Correspondence Address:
Anupama Bappal
Department of Ophthalmology, Yenepoya Medical College, Deralakatte, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcor.jcor_1_22

Rights and Permissions

Aim: The aim of this study was to assess the relief from pain afforded by orally administered 20% dextrose as an analgesic for the purpose of retinopathy of prematurity (ROP) screening. Setting and Study Design: This was an observational case–control subject study design. Materials and Methods: This study was performed over a period of 19 months during the first ROP screening. The readings of clinical and behavioral parameters of preterm babies were taken at baseline and monitored continuously during the screening procedure. The right eye was examined before administration of oral dextrose (WOD) and the left eye was examined after administration of dextrose orally (WD). Babies were given 2 ml of 20% dextrose orally with syringe. ROP screening was performed under topical anesthesia with binocular indirect ophthalmoscope. Pain score was calculated by premature infant pain profile scoring system. Results: One hundred and two babies participated in this study, of which 33 (32.35%) babies had a gestational age ≤32 weeks. Statistical analysis done using Wilcoxon signed-rank test showed significant P values for pain score (P < 0.001), heart rate (P < 0.05), oxygen saturation (P < 0.05), and behavioral parameters (P < 0.001) for WOD and WD. Pain score, WOD, and WD in babies ≤32 and >32 weeks were also significant (P < 0.001) for pain score, heart rate (<0.05), and behavioral parameters except for oxygen saturation (P > 0.05) (Mann–Whitney U test). Conclusions: Oral dextrose has a significant role in reducing pain, during ROP screening, but does not alleviate pain completely. The within-subject study design ensured close to identical baseline parameters, thereby providing better internal reliability of the study.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed310    
    Printed10    
    Emailed0    
    PDF Downloaded46    
    Comments [Add]    

Recommend this journal